Measurement of Trace Elements in Proteins Extracted from Liver by Size Exclusion Chromatography-Inductively Coupled Plasma-Mass Spectrometry with a Magnetic Sector Mass Spectrometer

✍ Scribed by Jin Wang; Dawn Dreessen; Daniel R. Wiederin; R.S. Houk

• Publisher: Elsevier Science
• Year: 2001
• Tongue: English
• Weight: 109 KB
• Volume: 288
• Category: Article
• ISSN: 0003-2697
• DOI: 10.1006/abio.2000.4885

✦ Synopsis

Proteins are extracted from liver into aqueous buffer at pH 7 and separated by size exclusion chromatography (SEC). Inductively coupled plasma mass spectrometry (ICP-MS) with a magnetic sector mass spectrometer is used to identify those protein fractions that contain Cu,