Measurement of tissue lithium concentration by lithium magnetic resonance spectroscopy in patients with bipolar disorder : Laszlo Gyulai, M.D., Steven W. Wicklund, B.S., Robert Greenstein, M.D., Mark Bauer, M.D., Patrick Ciccione, M.D., Peter Whybrow, M.D., Joanne Zimmerman, R.N., Gyula Kovachich, Ph.D. Department of Psychiatry, Hospital of Pennyylvania (L.G., R.G., M.B., P.W.), Department of Psychiatry, Veterans Affairs Medical Center (R.G., P.C., J.Z., G.K.), and Department of Biochemistry and Biophysics, Magnetic Resonance Research Resource, University of Pennsylvania, Philadelphia, PA (L.G., S.W.W.), Medical College of wisconsin, Milwaukee, WI (S.W.W.).