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Measurement of Thromboxane B2in Platelet-Rich Human Plasma by Gas Chromatography–Mass Spectrometry and Gas Chromatography–Tandem Mass Spectrometry Following Extractive Pentafluorobenzyl Esterification

✍ Scribed by Kathrin S. Tewes; Dimitrios Tsikas; Frank-Mathias Gutzki; Jürgen C. Frölich


Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
83 KB
Volume
261
Category
Article
ISSN
0003-2697

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A gas-chromatography-mass spectrometry (GC-MS) method for the determination of plasma ibuprofen was developed. Plasma samples from cystic fibrosis (CF) patients receiving high-dose ibuprofen therapy were analyzed by GC-MS and the result compared to analysis by high-performance liquid chromatography