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Measurement of theophylline metabolites produced by reaction with hepatic microsome by high performance liquid chromatography following solid phase extraction

✍ Scribed by Hiroki Konishi; Akira Yamaji


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
444 KB
Volume
8
Category
Article
ISSN
0269-3879

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A high-performance liquid chromatographic system, combining solid-phase extraction and automated precolumn derivatization is described for the routine determination of methotrexate in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomit