## Abstract Mechanical loading plays a fundamental role in the physiological and pathological processes of articular cartilage. The application of dynamic compression to chondrocytes cultured in agarose, downregulates the release of nitric oxide (NO) and enhances cell proliferation and proteoglycan
Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression
โ Scribed by M.M Knight; S.A Ghori; D.A Lee; D.L Bader
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 294 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1350-4533
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## Abstract Articular cartilage is subjected to dynamic compressive loading that is known to influence chondrocyte metabolism. While the exact signalling mechanisms are unclear, it has been proposed that cell deformation plays a role and may stimulate a metabolic response through distinctive pathwa
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