✦ LIBER ✦

Measurement of the arterial concentration of Gd-DTPA using MRI: A step toward quantitative perfusion imaging

✍ Scribed by Thomas Fritz-Hansen; Egill Rostrup; Henrik B. W. Larsson; Lars Søndergaard; Poul Ring; Ole Henriksen

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 710 KB
Volume: 36
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910360209

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A noninvasive method using an inversion recovery turbo‐FLASH for dynamic measurement of the arterial input function represented by the bolus passage of Gd‐DTPA in the descending aorta is presented, and the results are compared with the input function obtained by arterial blood samples. A good accordance between the two input functions was found, indicating that it is possible to measure the input function to the myocardium using MRI. A variation between the two concentration curves of 5% at upslope, 2.7% at peak point, and <7% at downslope was found. The study also indicates that a short inversion time <250 ms has to be used to ensure correct measurement of peak concentration.

📜 SIMILAR VOLUMES

The MRI-measured arterial input function

The MRI-measured arterial input function resulting from a bolus injection of Gd-DTPA in a rat model of stroke slightly underestimates that of Gd-[14C]DTPA and marginally overestimates the blood-to-brain influx rate constant determined by Patlak plots

✍ Tavarekere N. Nagaraja; Kishor Karki; James R. Ewing; George W. Divine; Joseph D 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

## Abstract The hypothesis that the arterial input function (AIF) of gadolinium‐diethylenetriaminepentaacetic acid injected by intravenous bolus and measured by the change in the __T__~1~‐relaxation rate (Δ__R__~1~; __R__~1~ = 1/__T__~1~) of superior sagittal sinus blood (AIF‐I) approximates the AI