Stable isotope dilution analysis of N-ac
✍
Osama Y. Al-Dirbashi; Mohamed S. Rashed; Manhal A. Al-Mokhadab; Khalid Al-Qahtan
📂
Article
📅
2007
🏛
John Wiley and Sons
🌐
English
⚖ 176 KB
👁 2 views
## Abstract __N__‐acetylaspartic acid (NAA) is a specific urinary marker for Canavan disease, an autosomal recessive leukodystrophy. We developed a ‘dilute and shoot’ stable isotope dilution liquid chromatography tandem mass spectrometry (LC‐MS/MS) method for determination of NAA in urine. Deuterat