Measurement of preferential solvation of some glucans in mixed solvent systems by gel-permeation chromatography

✍ Scribed by Peggy R. Straub; David A. Brant

• Book ID: 102763989
• Publisher: Wiley (John Wiley & Sons)
• Year: 1980
• Tongue: English
• Weight: 910 KB
• Volume: 19
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.1980.360190313

✦ Synopsis

Preferential solvation of the glucans amylose, pullulan, and dextran in binary dimethylsulfoxide/water (DMSO/H20) solvent mixtures has been measured using gel-permeation chromatography. The preferential solvation behavior of the three glucans in DMSO/H20 solvent mixtures is indistinguishable in the experiments reported. In solvent mixtures with mol ratio DMSO/H20 less than 1:2, all three glucans are solvated preferentially by H20. The maximum extent of preferential solvation by HzO is about 2.5 mol HzO/mol of glucose residues. When the DMSO/H20 mol ratio exceeds 1:2, DMSO solvates the glucans preferentially to a maximum extent of about 1 mol DMSO/mol of glucose residues. An interpretation of the change in preferential solvation with mixed solvent composition is suggested in terms of the known characteristics of the binary solvent system, and the relationship of preferential solvation, reported here, to the absolute solvation of the glucan chains is discussed.