Considerations for osmolality measuremen
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Albert E. Schmelzer; Vivian M. deZengotita; William M. Miller
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Article
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2000
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John Wiley and Sons
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English
โ 215 KB
Osmolality increases with pCO 2 in bioreactors with pH control, and it has been shown that osmolality compensation by decreasing the basal NaCl concentration partially mitigates the adverse effects of elevated pCO 2 on animal cell growth, protein production, and glycosylation. Thus, measurement of o