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Measurement of liver adenine nucleotides and S-adenosyl amino acids by one-step high-performance liquid chromatography

✍ Scribed by Henriette Gourdeau; Robert Lavoie; John H. Grose; Luc Bélanger


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
262 KB
Volume
158
Category
Article
ISSN
0003-2697

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✦ Synopsis


A reverse-phase isocratic HPLC method is described for direct simultaneous assay of ATP, ADP. AMP, S-adenosylmethionine, S-adenosylhomocysteine, S-adenosylethionine, and other adenine derivatives in liver microbiopsies. The procedure was tested in conditions which alter the hepatic content of adenine nucleotides and sulfur-adenosyl amino acids in humans, rats, and gUinea pig.%


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