Measurement of Intracellular Oxygen Concentration During Photodynamic Therapy in vitro
โ Scribed by Weston, Mark A.; Patterson, Michael S.
- Book ID
- 125510973
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 314 KB
- Category
- Article
- ISSN
- 0031-8655
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Photodynamically induced oxygen depletion has been measured in an Ehrlich ascites mouse tumor cell line using a Clark-type electrode. Cells are loaded with aluminum phthalocyanines, sulfonated to different degrees (A1PcS(n), n = 0,2,3,4) and consisting of various isomeric species. Different cell lin
Tissue oxygenation is one of the key dosimetric factors involved in the application of photodynamic therapy (PDT). However, quantitative studies of oxygenation levels at and surrounding the treatment site have been lacking both before, during and after treatment. With the recent development of sensi
## Abstract [O~2~] was measured in the embedding material (alginate) in a typical apparatus for conducting studies of viable cells with NMR, using low frequency EPR. In suspension cultures respiration was independent of [O~2~] in the perfusing media down to about 1 ฮผM while in alginate beads, the c