## Abstract Arterial wall shear stress is widely believed to influence the formation and growth of atherosclerotic plaque; however, there is currently no gold standard for its in vivo measurement. The use of phase contrast MRI has proved to be challenging due to partialโvolume effects and inadequat
Measurement of fluid-shear rate by fourier-encoded velocity imaging
โ Scribed by Richard Frayne; Brian K. Rutt
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 989 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0740-3194
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โฆ Synopsis
Abstract
A new technique for estimating the blood fluid shear rate at the vessel wall is presented. The technique uses Fourierโencoded velocity imaging to determine the velocity distribution within a spatial element (voxel) that straddles the bloodvessel wall interface. By appropriate processing, the velocity distribution (1) can determine the location of the wallโblood interface within the voxel and (2) estimate the velocity profile across the spatial extent of the voxel. From this information, accurate estimates of fluid shear rate may be obtained. Simulations are presented to illustrate this technique and to show the effects of various error sources, including differences in proton densities between blood and wall tissues and flowโrelated signal changes. Experimental evidence obtained for steady flow in straight tubes is also presented in support of the technique. The mean error in the experimental shear rate estimates found using the proposed technique was โ15%. This represents a significant improvement over estimates obtained by extrapolation of the velocity profile over multiple voxels (mean error of โ73%).
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