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Measurement of dopamine D2 receptors in living human brain using [11C]raclopride with ultra-high specific radioactivity

✍ Scribed by Yota Fujimura; Hiroshi Ito; Hidehiko Takahashi; Fumihiko Yasuno; Yoko Ikoma; Ming-Rong Zhang; Shinichiro Nanko; Kazutoshi Suzuki; Tetsuya Suhara


Book ID
116799573
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
352 KB
Volume
37
Category
Article
ISSN
0969-8051

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Stereoselective binding of 11C-racloprid
✍ L. Farde; S. Pauli; H. Hall; L. Eriksson; C. Halldin; T. HΓΆgberg; L. Nilsson; I. πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 803 KB

The selective D2-dopamine receptor antagonist raclopride and its pharmacologically inactive (R)-enantiomer FLB472 were labelled with 11C and used in a study with positron emission tomography to examine the stereoselectivity of 11C-raclopride binding to central D2-dopamine receptors in three healthy