Measurement of cell-bound complement activation products enhances diagnostic performance in systemic lupus erythematosus
β Scribed by Kalunian, Kenneth C.; Chatham, W. Winn; Massarotti, Elena M.; Reyes-Thomas, Joyce; Harris, Cole; Furie, Richard A.; Chitkara, Puja; Putterman, Chaim; Gross, Rachel L.; Somers, Emily C.; Kirou, Kyriakos A.; Ramsey-Goldman, Rosalind; Hsieh, Christine; Buyon, Jill P.; Dervieux, Thierry; Weinstein, Arthur
- Book ID
- 118752679
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 127 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
## Abstract __Objective.__ To determine whether increased levels of the complement split products generated in the activation of the alternative or classical pathway accompany more severe disease activity in patients with systemic lupus erythematosus (SLE) and whether these measurements are useful
## Abstract It has recently been found that excessive serum Bβcell activating factor (BAFF) production triggers severe autoimmune disorders in mice resembling systemic lupus erythematosus (SLE). Whether such dysregulation in circulating levels of BAFF results from overexpression of BAFF gene in cli