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Measurement of bone resorption (BR) and formation (BF) in rats using the urinary pharmacokinetic of fluoride (F)

✍ Scribed by M. Lupo; B. Garcia; H. Moreno; A. Rigalli

Book ID
116325004
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
51 KB
Volume
49
Category
Article
ISSN
8756-3282

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This report presents a pharmacokinetic model in the rat and rabbit of the direct quantification of mature bone resorption in vivo. This is based on a first-order reaction rate describing the release of [3H]tetracycline from bone. Compared with the previous method, the model has two new means of expr