𝔖 Bobbio Scriptorium
✦   LIBER   ✦

MDR1 (multidrug resistence 1) can regulate GCS (glucosylceramide synthase) in breast cancer cells

✍ Scribed by Xiaofang Zhang; Xiaojuan Wu; Juan Li; Yanlin Sun; Peng Gao; Cuijuan Zhang; Hui Zhang; Gengyin Zhou


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
466 KB
Volume
104
Category
Article
ISSN
0022-4790

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Regulation of multidrug resistance gene
✍ M. Tien Kuo; Joanne Julian; Farah Husain; Renduo Song; Daniel D. Carson πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 1024 KB

## Abstract The mammalian uterine epithelium (UE) undergoes drastic physiological and morphological changes during pregnancy. Steady‐state levels of murine __mdr1b__ mRNA, transcribed from a multidrug resistance gene encoding a membrane protein which functions as a transporter of lipophilic cytotox

MRP1 and glucosylceramide are coordinate
✍ Karin Klappe; John W.J. Hinrichs; Bart-Jan Kroesen; Hannie Sietsma; Jan Willem K πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 295 KB

## Abstract Previously we have described a novel multidrug‐resistant cell line, HT29^col^, which displayed over expression of the multidrug‐resistance protein 1 (MRP1) and an altered sphingolipid composition, including enhanced levels of glucosylceramide (GlcCer; Kok JW, Veldman RJ, Klappe K, Konin

Annamycin circumvents resistance mediate
✍ Roman Perez-Soler; Nouri Neamati; Yiyu Zou; Erasmus Schneider; L. Austin Doyle; πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 144 KB πŸ‘ 2 views

Annamycin (Ann) is a highly lipophilic anthracycline antibiotic that has been shown to circumvent MDR-1 both in vitro and in vivo. A liposomal formulation of Ann is currently in phase I clinical trials. The multidrug resistance-associated protein (MRP) has been found to be over-expressed in some hum

Lack of modulation of MDR1 gene expressi
✍ Amadeo M. Parissenti; Brian R. Gannon; David J. Villeneuve; Angela F. Kirwan-rhu πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 172 KB πŸ‘ 2 views

The drug transporter P-glycoprotein (P-gp) appears to play an important role in the ability of tumor cells to evade killing by chemotherapeutic agents. Using pharmacological inhibitors of cAMP-dependent protein kinase (PKA), it has been suggested that, similar to rodent model systems, the human P-gp