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MDR1 modulators improve the chemotherapy response of human hepatoblastoma to doxorubicin in vitro

✍ Scribed by Steven Warmann; Gudrun G[ouml ]hring; Birgit Teichmann; Heinz Geerlings; J[ouml ]rg Fuchs

Book ID
117827697
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
171 KB
Volume
37
Category
Article
ISSN
0022-3468

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## Abstract Multidrug resistance, the phenomenon by which cells treated with a drug become resistant to the cytotoxic effect of a variety of other structurally and functionally unrelated drugs, is often associated with the expression of P‐glycoprotein, an efflux membrane pump coded by the __MDR1 (A