𝔖 Bobbio Scriptorium
✦   LIBER   ✦

MDM2 SNP309 promoter polymorphism, an independent prognostic factor in chronic lymphocytic leukemia

✍ Scribed by Kerstin Willander; Jonas Ungerbäck; Karin Karlsson; Mats Fredrikson; Peter Söderkvist; Mats Linderholm


Book ID
114794795
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
138 KB
Volume
85
Category
Article
ISSN
0902-4441

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Investigation of an NQO1 polymorphism as
✍ Asher Begleiter; Donna Hewitt; Spencer B. Gibson; James B. Johnston 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 395 KB

NAD(P)H:quinoneoxidoreductase 1 (NQO1) inhibits some cancers and increases p53 and apoptosis in cells. Due to an inactivating polymorphism, 10% of humans have no NQO1 activity. A case:control study suggested that chronic lymphocytic leukemia (CLL) patients may have an increased incidence of the NQO1