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MDM2 SNP309 contributes to tumor susceptibility: A meta-analysis

✍ Scribed by Xiaoman Wo; Dong Han; Haiming Sun; Yang Liu; Xiangning Meng; Jing Bai; Feng Chen; Yang Yu; Yan Jin; Songbin Fu

Book ID: 116647948
Publisher: Elsevier
Year: 2011
Tongue: Chinese
Weight: 588 KB
Volume: 38
Category: Article
ISSN: 1673-8527
DOI: 10.1016/j.jgg.2011.07.005

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## Abstract Murine double minute 2 (MDM2) is a negative regulator of the tumor suppressor gene __p53__. Single nucleotide polymorphisms in __MDM2__ and __p53__ can affect patient's response to chemotherapy as well as overall survival of many cancers. This study aimed to assess the associations betw