𝔖 Bobbio Scriptorium
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MDM2 polymorphisms and cancer risk in basal cell carcinoma: reply from authors

✍ Scribed by S. Wilkening; K. Hemminki; R. Kumar

Book ID
108669862
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
60 KB
Volume
158
Category
Article
ISSN
0007-0963

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## Abstract Abnormalities of the tumor suppressor TP53 pathway are critical in the development of many cancers since it regulates cell cycle components and apoptosis. Murine double minute‐2 (MDM2) protein is a central node in the p53 pathway and a direct negative regulator of p53. The __MDM2 SNP309