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Mdm2 is a novel activator of ApoCIII promoter which is antagonized by p53 and SHP inhibition

✍ Scribed by Zhihong Yang; Yuxia Zhang; Li Wang

Book ID
116302757
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
324 KB
Volume
417
Category
Article
ISSN
0006-291X

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## Abstract Cross‐talk between the two transcription factors, p53 and hypoxia inducible factor 1Ξ± (HIF1A), is important in different pathophysiological conditions (Hammond and Giaccia, 2006, Clin Cancer Res 12:5007–5009) such as in the transition from myocardial hypertrophy to cardiac dilatation an