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MDM2 and MDM4: p53 regulators as targets in anticancer therapy

โœ Scribed by Franck Toledo; Geoffrey M. Wahl


Book ID
116307383
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
274 KB
Volume
39
Category
Article
ISSN
1357-2725

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## Abstract The powerful tumor suppressor p53 takes charge of a regulatory network to guard over the living cells from harmful effect of different forms of stress and eradicate the tumor cells for normal physiological condition maintenance. However the antitumor function of p53 is often attenuated