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MCF-7 breast carcinoma cells express ryanodine receptor type 1: functional characterization and subcellular localization

✍ Scribed by Carlos Saldaña; Mauricio Díaz-Muñoz; Anaid Antaramián; Adriana González-Gallardo; Pablo García-Solís; Verónica Morales-Tlalpan


Book ID
106458746
Publisher
Springer
Year
2008
Tongue
English
Weight
450 KB
Volume
323
Category
Article
ISSN
0300-8177

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Cytofluorimetric and reverse-transcription polymerase chain reaction (RT-PCR) analysis showed that adriamycinresistant (ADR R ), but not sensitive (WT), MCF-7 human mammary carcinoma cell lines express a4b1 and a5b1 integrins. ADR R cells adhere to fibronectin (FN), and only a5b1 is involved in cell