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MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas

✍ Scribed by Per Helsing; Dag A Nymoen; Helge Rootwelt; Mari Vårdal; Lars A. Akslen; Anders Molven; Per A. Andresen


Book ID
112095585
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
750 KB
Volume
51
Category
Article
ISSN
1045-2257

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## Abstract The presence of multiple primary cutaneous melanomas (MPM) has been advocated as guidance to identifying melanoma families. Frequencies of __CDKN2A__ mutations in materials of sporadic MPM cases from pigmented lesion clinics vary between 8 and 15%. Patients with MPM have therefore been