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MC13-0004 Prognostic significance of MGMT and IDH1 in patients with secondary glioblastoma

✍ Scribed by Bie, L.; Zhang, X.; Li, M.


Book ID
122123715
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
58 KB
Volume
49
Category
Article
ISSN
0959-8049

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## Abstract Alterations in the signal transduction pathways are key mechanisms in the pathogenesis of __de novo__ glioblastoma multiforme (GBM), which are also involved in the resistance to chemo‐ and radiotherapy. Here, we analyzed the methylation status and mRNA expression of suppressor of cytoki