𝔖 Bobbio Scriptorium
✦   LIBER   ✦

MC Polyomavirus Is Frequently Present in Merkel Cell Carcinoma of European Patients

✍ Scribed by Becker, Jürgen C; Houben, Roland; Ugurel, Selma; Trefzer, Uwe; Pföhler, Claudia; Schrama, David

Book ID
109875179
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
110 KB
Volume
129
Category
Article
ISSN
0022-202X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Frequent occurrence of RASSF1A promoter
Frequent occurrence of RASSF1A promoter hypermethylation and merkel cell polyomavirus in merkel cell carcinoma
✍ Peter Helmbold; Christoph Lahtz; Alexander Enk; Peter Herrmann-Trost; Wolfgang C 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

## Abstract Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. It has recently been reported that integration of a Merkel cell polyomavirus (MCPyV) in __receptor tyrosine phosphates type G__ (__PTPRG__) gene occurs in MCC, and that viral infections are associated with ep

Merkel cell polyomavirus sequences are f
Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients
✍ Ahmad Kassem; Kristin Technau; Anna Kordelia Kurz; Deepa Pantulu; Marie Löning; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 111 KB

## Abstract Recently, a new human polyoma virus has been identified in Merkel cell carcinomas (MCC). MCC is a highly aggressive neuroendocrine nonmelanoma skin cancer (NMSC) associated with immunosuppression. Clonal integration of this virus which was termed Merkel cell polyoma virus (MCPyV) was re

An intact retinoblastoma protein-binding
An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells
✍ Roland Houben; Christian Adam; Anne Baeurle; Sonja Hesbacher; Johannes Grimm; Sa 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 934 KB

## Abstract Merkel cell carcinoma (MCC) is a highly aggressive skin cancer that frequently harbours Merkel cell polyomavirus (MCV) DNA integrated in the genome of the tumor cells. In our study, we elaborate our recent finding that MCV‐positive MCC cell lines require the expression of the viral T an