A cloned human hepatoma cell line (Li-7A), possessing epidermal growth factor (EGF) receptors numbering in the range of 10-20 pmol/106 cells, was inhibited in its growth by EGF as well as an antagonist monoclonal antibody (MoAb) to the EGF receptor. The mode of action of the two ligands of EGF recep
β¦ LIBER β¦
Maximizing Human Epidermal Growth Factor Receptor 2 Inhibition: A New Oncologic Paradigm in the Era of Targeted Therapy
β Scribed by Olson, E. M.
- Book ID
- 111678244
- Publisher
- American Society of Clinical Oncology
- Year
- 2012
- Tongue
- English
- Weight
- 111 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0732-183X
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## Abstract ## BACKGROUND Breast cancers that are negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) (triple negative [TN]) have been associated with highβgrade histology, aggressive clinical behavior, and poor survival. It has been
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