✦ LIBER ✦

Maximising use of in vitro ADMET tools to predict in vivo bioavailability and safety

✍ Scribed by Wang, Jianling; Urban, Laszlo; Bojanic, Dejan

Book ID: 115540441
Publisher: Informa plc
Year: 2007
Tongue: English
Weight: 731 KB
Volume: 3
Category: Article
ISSN: 1742-5255
DOI: 10.1517/17425255.3.5.641

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Recombinant in vitro tools to predict dr

Recombinant in vitro tools to predict drug metabolism and safety

✍ Thomas Friedberg 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 127 KB

Predictive ADMET (Integrative Approaches

Predictive ADMET (Integrative Approaches in Drug Discovery and Development) || In Vitro - In Silico Tools to Predict Pharmacokinetics of Poorly Soluble Drug Compounds

✍ Wang, Jianling; Urban, Laszlo 📂 Article 📅 2014 🏛 John Wiley & Sons, Inc. ⚖ 862 KB

Physiological models are good tools to p

Physiological models are good tools to predict rat bioavailability of EF5154 prodrugs from in vitro intestinal parameters

✍ Masahiro Nomoto; Tomoko Tatebayashi; Jun Morita; Hisashi Suzuki; Kazumasa Aizawa 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

There are only a few reports on the methods that predict in vivo bioavailability from in vitro intestinal parameters. In the present study, we constructed physiological models where we examined if in vivo rat bioavailability was predictable from in vitro intestinal parameters using prodrugs of EF515

Predictive ADMET (Integrative Approaches

Predictive ADMET (Integrative Approaches in Drug Discovery and Development) || Practical Anticipation of Human Efficacious Doses and Pharmacokinetics Using Preclinical In Vitro and in Vivo Data

✍ Wang, Jianling; Urban, Laszlo 📂 Article 📅 2014 🏛 John Wiley & Sons, Inc. ⚖ 707 KB

Volume to dissolve applied dose (VDAD) a

Volume to dissolve applied dose (VDAD) and apparent dissolution rate (ADR): Tools to predict in vivo bioavailability from orally applied drug suspensions

✍ Uwe Muenster; Christian Pelzetter; Thomas Backensfeld; Andreas Ohm; Thomas Kuhlm 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 558 KB

Predictive ADMET (Integrative Approaches

Predictive ADMET (Integrative Approaches in Drug Discovery and Development) || Integrated Assessment and Clinical Translation of In Vitro Off-Target Safety Pharmacology Risks

✍ Wang, Jianling; Urban, Laszlo 📂 Article 📅 2014 🏛 John Wiley & Sons, Inc. ⚖ 157 KB