Maurotoxin, a four disulfide bridge toxin from Scorpio maurus venom: purification, structure and action on potassium channels

Solution structure of maurotoxin, a scor

Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels

✍ E. Blanc; J.M. Sabatier; R. Kharrat; S. Meunier; M. El Ayeb; J. Van Rietschoten; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 488 KB 👁 2 views

Maurotoxin (MTX), purified from the scorpionid Scorpio maurus is a potent ligand for potassium channels. It shows a broad specificity as being active on Kv1.1 (Kd ‫؍‬ 37 nM), Kv1.2 (Kd ‫؍‬ 0.8 nM), Kv1.3 (Kd ‫؍‬ 150 nM) voltage-gated potassium channels, as well as on small-conductance calcium-activa