Maurice M. Black, M.D. : In memoriam
โ Scribed by Reinhard E. Zachrau
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 74 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
died at age 78 years. His entire professional life, which spanned more than 5 decades, was devoted to research, patient care, and the education of future physicians. In collaboration with many colleagues throughout his career, he always-to use his own words-''sought to see more than common vision, truths beyond what seemed to be.'' His research was aimed at advancing the understanding of cancer, particularly mammary carcinogenesis and the biologic behavior of breast carcinoma. In the last 2 decades, the main focus of his research was the dynamics of the interaction between cancer aggressiveness and host response mechanisms, involving in particular direct measurements of cell-mediated immune reactivity in patients against their own cancer cells, the evaluation of the prognostic significance of that data, and the utility of the data in the individualization of adjuvant therapy. Most importantly, the accrued observations proved consistent with the evolved concept that induced specific cell-mediated immunity would impede in situ-to-invasive breast carcinoma progression, and thus made immunoprophylaxis of invasive breast carcinoma an attainable goal. His last publication appeared in Cancer on August 15, 1996.
Dr. Black received his undergraduate education at Long Island University and graduated in 1937 with honors in biology. Subsequently, he spent a year conducting research in Robert Chambers' laboratory of cellular physiology at New York University. His work there led to his first publication on the nuclear structure of cells in May of 1941, co-authored with his mentor. In 1939, he entered New York Medical College and, as a medical student, engaged in research on physiologic properties of nerve fibers and energy mechanisms in cancer tissues. In 1943, during his internship at Kings County Hospital in Brooklyn, New York, he initiated studies of the effects of enzyme inhibitors on leukemia patients. These studies were interrupted by his military service as a captain in the Medical Corps from 1944 to 1946, during which time he was
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