Maturation of the GFAP-immunopositive glial network is delayed in the olfactory bulbs of rats subjected to early, low-dose X-irradiation
✍ Scribed by Prof. Ferenc Hajós; Melinda Mészáros; Norbert Halász
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 865 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0894-1491
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Young rats were subjected to low‐level, repeated doses of x‐irradiation from a Co^60^ source and examined for the presence and arrangement of their GFAP‐immunopositive system at the light and electron microscopic levels. In 2‐week‐old control rats, labelled cells were already distributed homogeneously throughout the bulb, while in the experimental animal, a (newborn‐ and early postnatal‐type) radial arrangement of immunoreactive fibres continued to persist even until the end of the fourth postnatal week. This delay in the maturation of the GFAP‐immunopositive glial system may contribute to the hindered development of the bulbar neurones, neuronal connections, and field potentials, as found in earlier studies.