Up-regulation of cyclin D1 occurs in apo
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Kazuhisa Sakai; Kazuhiko Suzuki; Shuuitsu Tanaka; Tatsuro Koike
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Article
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1999
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John Wiley and Sons
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English
β 343 KB
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Cerebellar granule neurons isolated from 7-day-old rats and cultured in normal medium undergo apoptosis, but remain healthy under depolarizing conditions with elevated K Ψ (ΠΌ25 mM) or in the presence of brain-derived neurotrophic factor. Northern blot analysis showed that cyclin D1 mRNA was upregula