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Maturation delay of germ cells in fetuses with trisomy 21 results in increased risk for the development of testicular germ cell tumors

โœ Scribed by Martine Cools; Friedemann Honecker; Hans Stoop; Joris D. Veltman; Ronald R. de Krijger; Ewout Steyerberg; Katja P. Wolffenbuttel; Carsten Bokemeyer; Yun-Fai Chris Lau; Stenvert L.S. Drop; Leendert H.J. Looijenga


Book ID
116534072
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
786 KB
Volume
37
Category
Article
ISSN
1532-8392

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## Background: Testicular germ cell tumors are highly curable. however, 10-30% of patients have recurrence after initial treatment. the time-course of recurrence has implications for the duration of follow-up. this study was undertaken to assess the risk and time-course of recurrence and to identif