Matrix synthesis and degradation in human intervertebral disc degeneration
✍ Scribed by Le Maitre, C.L.; Pockert, A.; Buttle, D.J.; Freemont, A.J.; Hoyland, J.A.
- Book ID
- 118007283
- Publisher
- Portland Press
- Year
- 2007
- Tongue
- English
- Weight
- 119 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0300-5127
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## Abstract Calcification is a pathological process that may lead to impairment of nutrient supply and disc metabolism in degenerative and scoliotic intervertebral discs (IVDs). The purpose of this study was to assess the calcification potential of IVDs in degenerative disc disease (DDD) and adoles
## Abstract Human intervertebral disc when maintained in organ culture released a latent casein‐degrading metalloproteinase into the medium in a manner analogous to cultures of human cartilage. This enzyme was demonstrated to be immunologically identical to prostromelysin. It was also found that th