Matrix proteoglycans are markedly affected in advanced laryngeal squamous cell carcinoma
โ Scribed by Spyros S Skandalis; Achilleas D Theocharis; Dimitrios A Theocharis; Theodoros Papadas; Demitrios H Vynios; Nickoletta Papageorgakopoulou
- Book ID
- 116270219
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 790 KB
- Volume
- 1689
- Category
- Article
- ISSN
- 0925-4439
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The current treatment paradigm for patients with advanced laryngeal squamous cell carcinoma continues to evolve. The authors assembled a panel of experts from the fields of medical oncology, radiation oncology, and surgery to discuss treatment options and to defend their positions.
## Abstract ## Background Proteins regulating the cell cycle and cell death are frequently abnormally expressed in cancer. Several of these, particularly p53 and Bclโ2, have been widely suggested as possible prognostic markers in diverse human malignancies. Their role in predicting outcome in squa