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Matrix Precoated Targets for Direct Lipid Analysis and Imaging of Tissue

✍ Scribed by Yang, Junhai; Caprioli, Richard M.


Book ID
119961056
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
522 KB
Volume
85
Category
Article
ISSN
0003-2700

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## Abstract Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) has been used to directly analyze and image pharmaceutical compounds in intact tissue. The anti‐tumor drug SCH 226374 was unambiguously determined in mouse tumor tissue using MALDI‐QqTOFMS (QSTAR) by monitoring the