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Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in the respiratory tract: Potential implications in asthma and other lung diseases

✍ Scribed by Maud M. Gueders; Jean-Michel Foidart; Agnes Noel; Didier D. Cataldo


Book ID
113585933
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
211 KB
Volume
533
Category
Article
ISSN
0014-2999

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Degradation of the extracellular matrix (ECM) is an essential step in tumour invasion and metastasis. The matrix metalloproteinases (MMPs) each have different substrate specificities within the ECM and are important in its degradation. MMP activity is dependent on the levels of activated MMP and tis