The glucocorticoid dexamethasone (Dex) induces a decline in protein synthesis and protein content in tissue cultured, avian skeletal muscle cells, and this atrophy is attenuated by repetitive mechanical stretch. Since the prostaglandin synthesis inhibitor indomethacin mitigated this stretch attenuat
✦ LIBER ✦
Matrix metalloproteinases are involved in mechanical stretch–induced activation of skeletal muscle satellite cells
✍ Scribed by Michiko Yamada; Ryuichi Tatsumi; Takashi Kikuiri; Shinpei Okamoto; Shinsuke Nonoshita; Wataru Mizunoya; Yoshihide Ikeuchi; Hiroaki Shimokawa; Kenji Sunagawa; Ronald E. Allen
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 182 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0148-639X
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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor