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Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases

โœ Scribed by Tim Cawston

Book ID
114381988
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
156 KB
Volume
4
Category
Article
ISSN
1357-4310

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Degradation of the extracellular matrix (ECM) is an essential step in tumour invasion and metastasis. The matrix metalloproteinases (MMPs) each have different substrate specificities within the ECM and are important in its degradation. MMP activity is dependent on the levels of activated MMP and tis