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Matrix metalloproteinases 2 and 9 in oral squamous cell carcinomas: manifestation and localization of their activity

✍ Scribed by Keizo Kato; Akira Hara; Toshiya Kuno; Nami Kitaori; Zhi Huilan; Hideki Mori; Makoto Toida; Toshiyuki Shibata

Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
476 KB
Volume
131
Category
Article
ISSN
1432-1335

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## Abstract The mechanisms by which c‐__erb__B‐dependent signaling contribute to the invasive potential of HNSCC remain to be fully elucidated. We have previously shown that c‐__erb__B autocrine and/or paracrine stimulation upregulates MMP‐9 but has no effect on the related gelatinase, MMP‐2. BTC,