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Matrix metalloproteinase inhibition improves survival in an orthotopic model of human pancreatic cancer

โœ Scribed by Emmanuel E. Zervos; Michael G. Franz; Khaled F. Salhab; Alexis E. Shafii; Julian Menendes; William R. Gower; Alexander S. Rosemurgy

Book ID
108487939
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
527 KB
Volume
4
Category
Article
ISSN
1091-255X

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BACKGROUND. Increased concentrations of metalloproteinases are associated with the invasive and metastatic behavior of several human malignant tumors. Normally, enzymatic activity is tightly regulated by nonspecific mechanisms and specific inhibitors. The aim of the study was to determine the potent