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Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-α inhibitor

✍ Scribed by John M Clements; Judy A Cossins; Graham M.A Wells; Dominic J Corkill; Karen Helfrich; L.Mike Wood; Rod Pigott; Gary Stabler; George A Ward; Andrew J.H Gearing; Karen M Miller


Book ID
117337396
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
475 KB
Volume
74
Category
Article
ISSN
0165-5728

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**Summary** An inflammatory response occurs during cardiac surgery involving cardiopulmonary bypass. Matrix metalloproteinase‐9 is an enzyme involved in cytokine processing and leucocyte extravasation. It is secreted as a pro‐enzyme in response to several inflammatory mediators and is inhibited by e