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Matrix metalloproteinase-1 expression induced by IL-1β requires acid sphingomyelinase

✍ Scribed by Jessica Bauer; Christian Huy; Julia Brenmoehl; Florian Obermeier; Jürgen Bock

Book ID: 113621242
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 608 KB
Volume: 583
Category: Article
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2009.02.008

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## Abstract Obesity is associated with a chronic low‐grade inflammation and increased macrophage infiltration in adipose tissue. Matrix metalloproteinases (MMPs) are involved in adipose tissue remodeling and inflammatory responses in obesity. This study investigated whether macrophage‐derived facto