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Matrix Metalloprotease Inhibitors Suppress Initiation and Progression of Chondrogenic Differentiation of Mesenchymal Stromal Cells In Vitro

✍ Scribed by Bertram, Helge; Boeuf, Stephane; Wachters, Jasper; Boehmer, Sandra; Heisel, Christian; Hofmann, Michael W.; Piecha, Dorothea; Richter, Wiltrud


Book ID
120271641
Publisher
Mary Ann Liebert
Year
2009
Tongue
English
Weight
482 KB
Volume
18
Category
Article
ISSN
1547-3287

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This study addresses the role of bone morphogenetic protein-7 (BMP-7) in chondrogenic and osteogenic differentiation of human bone marrow multipotent mesenchymal stromal cells (BM MSCs) in vitro. BM MSCs were expanded and differentiated in the presence or absence of BMP-7 in monolayer and three-dime