An evaluation of mathematical models for
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Guoping Lian; Longjian Chen; Lujia Han
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Article
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2008
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John Wiley and Sons
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English
β 204 KB
A number of mathematical models have been proposed for predicting skin permeability, mostly empirical and very few are deterministic. Early empirical models use simple lipophilicity parameters. The recent trend is to use more complicated molecular structure descriptors. There has been much debate on