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Mathematical models of cytotoxic T-lymphocyte killing

✍ Scribed by Regoes, Roland R; Yates, Andrew; Antia, Rustom


Book ID
110041407
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
221 KB
Volume
85
Category
Article
ISSN
0818-9641

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Cytotoxic T lymphocytes in HIV-1 infecti
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ytotoxic T lymphocytes (CTLs) are part of the major host defence against trespassing intracellular pathogens. It has been shown in vitro that human immunodeficiency virus type 1 (HIV-1)specific CTLs can eliminate virus-infected cells via MHC class I-restricted killing 1,2 and can interfere with HIV-