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Mathematical modelling of fibre-enhanced perfusion inside a tissue-engineering bioreactor

✍ Scribed by Robert J. Whittaker; Richard Booth; Rosemary Dyson; Clare Bailey; Louise Parsons Chini; Shailesh Naire; Sevil Payvandi; Zimei Rong; Hannah Woollard; Linda J. Cummings; Sarah L. Waters; Lina Mawasse; Julian B. Chaudhuri; Marianne J. Ellis; Vipin Michael; Nicola J. Kuiper; Sarah Cartmell

Book ID
108196437
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
923 KB
Volume
256
Category
Article
ISSN
0022-5193

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## Abstract Perfusion bioreactors improve mass transfer in cell‐scaffold constructs. We developed a mathematical model to simulate nutrient flow through cellular constructs. Interactions among cell proliferation, nutrient consumption, and culture medium circulation were investigated. The model inco