Mathematical modeling of salt-gradient ion-exchange simulated moving bed chromatography for protein separations
β Scribed by Jian-gang Lu
- Book ID
- 111840094
- Publisher
- SP Zhejiang University Press
- Year
- 2004
- Tongue
- English
- Weight
- 553 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1009-3095
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π SIMILAR VOLUMES
## Abstract Protein elution curves in ion exchange chromatography (IEC) were simulated with a rate model. Three pure proteins and their mixture were used (Ξ±βlactalbumin, BSA, and conalbumin) under different operational conditions. The anionic matrix QβSepharose FF was used packed in a 1βmL column.
## Abstract Liquidβsolid circulating fluidized bed (LSCFB) is an integrated twoβcolumn (downcomer and riser) system which can accommodate two separate processes (adsorption and desorption) in the same unit with continuous circulation of the solid particles between the two columns. In this study, a
Elution curves in ionic exchange chromatography (IEC) for a three-protein mixture (alpha-lactoalbumin, ovalbumin, and beta-lactoglobulin), carried out under different flow rates and ionic strength conditions, were simulated using two different mathematical models. These models were the Plate Model a