The mixing and heat transfer phenomena within rotating drum bioreactors (RDBs) used for solid-state fermentation processes are poorly studied. The potential for the establishment of axial temperature gradients within the substrate bed was explored using a heat transfer model. For growth of Aspergill
Mathematical model of heat transfer during solid-state fermentation in well-mixed rotating drum bioreactors
β Scribed by Deidre M Stuart; David A Mitchell
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2003
- Tongue
- English
- Weight
- 220 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0268-2575
- DOI
- 10.1002/jctb.920
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β¦ Synopsis
Abstract
We present a mathematical model that describes heat and mass transfer during solidβstate fermentation (SSF) of Aspergillus oryzae in a wellβmixed rotating drum bioreactor (RDB). In addition to the substrate bed and the headspace, the model recognises the bioreactor wall as a subsystem, allowing it to identify the role of this subsystem in heat removal from the bed. Model predictions agree well with previously published experimental data obtained in a rotating drum bioreactor of 0.19 m diameter and 0.85 m length, with maximum temperatures up to 15 Β°C greater than the incubation temperature being reached. The model offers insights into the rate limiting steps in heat removal, and how SSF performance might be improved in the experimental system. Copyright Β© 2003 Society of Chemical Industry
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A two-dimensional heat transfer model was validated against two experimental studies from the literature which describe the growth of Aspergillus niger during solid-state fermentation in packed bed bioreactors. With the same set of model parameters, the twodimensional model was able to describe both