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Mathematical basis of affected sib-pair analysis: an extension to X-linked loci

✍ Scribed by Yasuo Tsukamoto; Koichiro Komai; Ken Tsumiyama; Yoshitada Sakai; Shunichi Shiozawa


Book ID
106292275
Publisher
Springer
Year
2010
Tongue
English
Weight
239 KB
Volume
20
Category
Article
ISSN
1439-7595

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## Abstract It has been shown that two‐locus linkage analysis can, for some two‐locus disease models, be used to detect effects at disease loci that do not reach significance in a genome scan. However, few examples exist where two‐locus linkage has been successfully used to map genes. We study the